full transcript

From the Ted Talk by Adam Garske: How designing brand-new enzymes could change the world

Unscramble the Blue Letters

So, how would we go about designing an ezynme to realize these changes? Enzymes didn't evolve to celan dirty laundry, much less in cold water. But we can go to nature, and we can find a starting ponit. We can find an enzyme that has some starting activity, some clay that we can work with. So this is an example of such an enzyme, right here on the screen. And we can start playing with those amino acids, as I said, puntitg some letters in, taking some letters out, rearranging those. And in doing so, we can generate thousands of enzymes. And we can take those ezynems, and we can test them in little plates like this.

Open Cloze

So, how would we go about designing an ______ to realize these changes? Enzymes didn't evolve to _____ dirty laundry, much less in cold water. But we can go to nature, and we can find a starting _____. We can find an enzyme that has some starting activity, some clay that we can work with. So this is an example of such an enzyme, right here on the screen. And we can start playing with those amino acids, as I said, _______ some letters in, taking some letters out, rearranging those. And in doing so, we can generate thousands of enzymes. And we can take those _______, and we can test them in little plates like this.

Solution

  1. point
  2. putting
  3. enzyme
  4. clean
  5. enzymes

Original Text

So, how would we go about designing an enzyme to realize these changes? Enzymes didn't evolve to clean dirty laundry, much less in cold water. But we can go to nature, and we can find a starting point. We can find an enzyme that has some starting activity, some clay that we can work with. So this is an example of such an enzyme, right here on the screen. And we can start playing with those amino acids, as I said, putting some letters in, taking some letters out, rearranging those. And in doing so, we can generate thousands of enzymes. And we can take those enzymes, and we can test them in little plates like this.

Frequently Occurring Word Combinations

ngrams of length 2

collocation frequency
amino acids 7
common amino 3
cold water 3
bright red 2
quick zip 2
enzyme working 2
work properly 2
fun part 2
directed evolution 2
design enzymes 2
designing enzymes 2
laundry detergent 2
master protein 2
adding unnatural 2
unnatural amino 2
big news 2

ngrams of length 3

collocation frequency
adding unnatural amino 2
unnatural amino acids 2

ngrams of length 4

collocation frequency
adding unnatural amino acids 2

Important Words

  1. acids
  2. activity
  3. amino
  4. clay
  5. clean
  6. cold
  7. designing
  8. dirty
  9. enzyme
  10. enzymes
  11. evolve
  12. find
  13. generate
  14. laundry
  15. letters
  16. nature
  17. plates
  18. playing
  19. point
  20. putting
  21. realize
  22. rearranging
  23. screen
  24. start
  25. starting
  26. test
  27. thousands
  28. water
  29. work